海角破解版

Register: On-Demand Application of HSPCs in Cell Therapy Course

Sign up to access this free course on the application of HSPCs in translational clinical research and cell therapy manufacturing.

In this self-paced, virtual course, you will learn about the key workflow and compliance considerations for applying hematopoietic stem and progenitor cells (HSPCs) in cell therapy development. From the fundamentals of hematological disease and disease progression, to CD34+ cell sourcing and expansion, and selecting the right tools and assays, this course provides foundational knowledge on the use of HSPCs in cell therapy, while addressing current challenges and future opportunities for expanding access to hematopoietic cell therapies.

Content Developer Bios

Dr. Daniela Mora Ortiz, Product Manager, Hematology

Dr. Daniela Mora Ortiz, Product Manager, Hematology at 海角破解版 Technologies

Dr. Daniela Mora Ortiz is a Product Manager for the Hematology portfolio at 海角破解版 Technologies. She earned her medical degree in Mexico City and completed her specialization in Hematology and Hemotherapy at Hospital Vall d鈥橦ebron in Barcelona, Spain, where she gained clinical experience in hematological diseases, hematopoietic stem cell transplantation, and blood bank activities. Following her clinical training, she conducted research on pluripotent stem cell differentiation toward hematopoietic lineages and lung differentiation, developing expertise in stem cell biology and translational research. Since joining 海角破解版 in 2017, Dr. Mora Ortiz has held roles in education, lab management, scientific support, and product management, providing training, advanced technical support, troubleshooting, and consultation to researchers worldwide. She has worked extensively with hematopoietic, epithelial, and organoid culture systems, including intestinal, hepatic, pancreatic, neural, and lung models, as well as air鈥搇iquid interface (ALI) cultures. In her current role, she leads and supports cross-functional initiatives in hematology and cell and gene therapy, bridging clinical insight, scientific expertise, and product strategy to enable researchers to translate discoveries from bench to bedside. She is passionate about advancing hematology and cell and gene therapy research and about empowering scientists to translate innovation into meaningful clinical impact.

Dr. Jackie Damen, Principal Scientist, Scientific Support, Hematology

Dr. Karina McQueen, Senior Principal Scientist, Research and Development, Immunology

Dr. Tina Jeng, Scientist, Scientific Support, Hematology

Course Curriculum

Session 1: Introduction to Hematological Disease, Disease Progression, and Hematopoietic Cell Therapy Products
  • Fundamentals of hematopoiesis and how disruptions lead to blood diseases, including inherited disorders, myeloid diseases, and leukemias
  • Clonal hematopoiesis and its effects on disease progression
  • Differences between autologous and allogeneic cell therapies
  • Sources of HSPCs and applications in hematopoietic cell therapy
  • Advantages and disadvantages of the different HSPC sources in the treatment of hematological disease

Mini Quiz: Test Your Knowledge


Estimated time for completion: 55 minutes

Session 2: The Basics of HLA for Transplantation
  • The basics of human leukocyte antigen (HLA) and common types of donors
  • Common laboratory tests performed before and after transplantation, including crossmatch, chimerism, and measurable residual disease

Mini Quiz: Test Your Knowledge


Estimated time for completion: 23 minutes

Session 3: Hematopoietic Stem Cells: Considerations for Improving Cell Therapy Products
  • Regulators of hematopoietic stem cells (HSCs) and hematopoiesis
  • Required assays for testing phenotypic versus functional capabilities of the engraftable HSC
  • Using cytokines and small molecules to improve HSC expansion
  • Optimizing ex vivo HSC expansion during the manufacture of hematopoietic cell therapy products for transplantation

Mini Quiz: Test Your Knowledge


Estimated time for completion: 46 minutes

Session 4: Workflow and Compliance Considerations for Hematopoietic Cell Therapy Products (HCTPs)
  • Considerations for the expansion and editing of HSCs for cell and gene therapy products
  • Products and tools used in the production and evaluation of HSCs for cell therapy products
  • Evaluation of the potency, stability, and purity of HCTPs
  • Approaches for method development and validation of product potency for HCTPs

Mini Quiz: Test Your Knowledge


Estimated time for completion: 49 minutes

Session 5: Future Directions for hPSC-Derived Cell Products
  • Advantages and challenges of human pluripotent stem cell (hPSC)-derived cell products
  • Potential future applications for hPSC-derived hematopoietic cell products
  • Steps required to generate cell therapy products from human induced pluripotent stem cells (hiPSCs)

Mini Quiz: Test Your Knowledge


Estimated time for completion: 25 minutes

Final Assessment

Complete this final assessment to test your knowledge and receive a certificate following successful completion.


Estimated time for completion: 15 minutes

This on-demand course is divided into 5 sessions and a final assessment. Following completion of the course, trainees can choose to receive a certificate of completion. Note that this is not an accredited course and cannot be used to receive Continuing Education (CE) credits.